TREATMENTS
Polynucleotides
Advanced regenerative skin treatments to repair, hydrate and restore from within
Polynucleotides are advanced injectable treatments designed to repair and regenerate the skin at a cellular level.
Unlike traditional skin boosters, they work by stimulating tissue repair, improving skin quality and reducing inflammation, making them ideal for delicate areas such as the eyes, face and scalp.
At M&K Aesthetics, we offer both classic polynucleotides (PDRN) and advanced PN treatments such as Rejuran, allowing us to tailor results depending on your skin concerns.
Duration
Face: 30 minutes
Eyes: 35 minutes
Hair (Scalp): 60 minutes
Rejuran (Advanced PN): 45–75 minutes (depending on area)
(Topical numbing cream applied for comfort)
Treatment Options
2–3 sessions recommended
Spaced 2–4 weeks apart
Maintenance advised every 6–9 months
Downtime
Mild swelling, redness or small bumps may occur
Face / Eyes: 24–48 hours
Hair (Scalp): minimal downtime
Rejuran (Advanced PN): up to 48 hours
Price
PDRN — From £220br> PN - From £290
before / after
Real Results.
Real Confidence.
Types of Polynucleotides
Classic Polynucleotides (Face / Eyes / Hair)
(e.g. Vitaran, Plinest)
These are based on PDRN (Polydeoxyribonucleotide) and are ideal for:
- Skin hydration and glow
- Fine lines and early ageing
- Under-eye rejuvenation
- Acne-prone or sensitive skin
- Hair thinning and scalp health
ITALIC Perfect for improving overall skin quality and maintaining healthy skin.
Rejuran Healer — Advanced Polynucleotides
Rejuran is a more advanced form of polynucleotide treatment (PN), offering deeper regeneration and stronger anti-ageing effects.
Compared to standard PDRN, PN has:
- Higher purity
- More powerful tissue repair properties
- Greater collagen stimulation
ITALIC This is why Rejuran is considered a premium, next-generation regenerative treatment.
What’s the difference between PDRN and PN?
- PDRN (classic polynucleotides) → Focus on hydration, skin repair and soothing inflammation
- PN (Rejuran) → More advanced regeneration, stronger anti-ageing and structural improvement
ITALIC Think of PDRN as skin quality maintenance, and PN as deeper skin regeneration.
Areas we treat
- Face
- Under-eye area
- Neck
- Scalp (for hair thinning)
ITALIC Each treatment is tailored depending on the area and concern.
Treatment Plan
A course of 2–3 sessions is recommended, spaced 2–4 weeks apart.
Maintenance sessions are advised every 6–9 months.
Why choose Polynucleotides?
- Improves skin quality without adding volume
- Stimulates natural collagen production
- Reduces inflammation and redness
- Safe for delicate areas like under-eyes
- Suitable for most skin types
ITALIC Ideal for patients wanting natural, regenerative results.
Why choose M&K Aesthetics
- Use of premium brands (Vitaran, Plinest, Rejuran)
- Advanced injection techniques
- Bespoke treatment plans
- Focus on natural, long-term results
ITALIC We select the right type of polynucleotide based on your skin — not a one-size-fits-all approach.
FAQ
What is the difference between polynucleotides and Profhilo®?
Does the treatment hurt?
What is the downtime?
You may experience small bumps, redness or mild swelling for 24–48 hours.
Is Rejuran better than standard polynucleotides?
Rejuran is a more advanced treatment with stronger regenerative effects, which is why it is positioned as a premium option.
Can it help with under-eye dark circles?
Yes — polynucleotides are one of the best treatments for improving under-eye skin quality, fine lines and crepey skin.
Can it help with hair loss?
Yes — when injected into the scalp, polynucleotides help stimulate hair follicles and improve scalp health.
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