TREATMENTS

Polynucleotides

Advanced regenerative skin treatments to repair, hydrate and restore from within

Polynucleotides are advanced injectable treatments designed to repair and regenerate the skin at a cellular level.

Unlike traditional skin boosters, they work by stimulating tissue repair, improving skin quality and reducing inflammation, making them ideal for delicate areas such as the eyes, face and scalp.

At M&K Aesthetics, we offer both classic polynucleotides (PDRN) and advanced PN treatments such as Rejuran, allowing us to tailor results depending on your skin concerns.

Duration

Face: 30 minutes
Eyes: 35 minutes
Hair (Scalp): 60 minutes
Rejuran (Advanced PN): 45–75 minutes (depending on area)
(Topical numbing cream applied for comfort)

Treatment Options

2–3 sessions recommended
Spaced 2–4 weeks apart
Maintenance advised every 6–9 months

Downtime

Mild swelling, redness or small bumps may occur
Face / Eyes: 24–48 hours
Hair (Scalp): minimal downtime
Rejuran (Advanced PN): up to 48 hours

Price

PDRN — From £220br> PN - From £290

before / after

Real Results.
Real Confidence.

Types of Polynucleotides

Classic Polynucleotides (Face / Eyes / Hair)

(e.g. Vitaran, Plinest)

These are based on PDRN (Polydeoxyribonucleotide) and are ideal for:

Skin hydration and glow
Fine lines and early ageing
Under-eye rejuvenation
Acne-prone or sensitive skin
Hair thinning and scalp health

ITALIC Perfect for improving overall skin quality and maintaining healthy skin.

Rejuran Healer — Advanced Polynucleotides

Rejuran is a more advanced form of polynucleotide treatment (PN), offering deeper regeneration and stronger anti-ageing effects.

Compared to standard PDRN, PN has:

Higher purity
More powerful tissue repair properties
Greater collagen stimulation

ITALIC This is why Rejuran is considered a premium, next-generation regenerative treatment.

What’s the difference between PDRN and PN?

PDRN (classic polynucleotides) → Focus on hydration, skin repair and soothing inflammation
PN (Rejuran) → More advanced regeneration, stronger anti-ageing and structural improvement

ITALIC Think of PDRN as skin quality maintenance, and PN as deeper skin regeneration.

Areas we treat

Face
Under-eye area
Neck
Scalp (for hair thinning)

ITALIC Each treatment is tailored depending on the area and concern.

Treatment Plan

A course of 2–3 sessions is recommended, spaced 2–4 weeks apart.

Maintenance sessions are advised every 6–9 months.

Why choose Polynucleotides?

Improves skin quality without adding volume
Stimulates natural collagen production
Reduces inflammation and redness
Safe for delicate areas like under-eyes
Suitable for most skin types

ITALIC Ideal for patients wanting natural, regenerative results.

Why choose M&K Aesthetics

Use of premium brands (Vitaran, Plinest, Rejuran)
Advanced injection techniques
Bespoke treatment plans
Focus on natural, long-term results

ITALIC We select the right type of polynucleotide based on your skin — not a one-size-fits-all approach.

FAQ

What is the difference between polynucleotides and Profhilo®?

Profhilo hydrates and stimulates collagen, while polynucleotides actively repair and regenerate damaged skin.

Does the treatment hurt?

A topical numbing cream is applied to keep the treatment comfortable.

What is the downtime?

You may experience small bumps, redness or mild swelling for 24–48 hours.

Is Rejuran better than standard polynucleotides?

Rejuran is a more advanced treatment with stronger regenerative effects, which is why it is positioned as a premium option.

Can it help with under-eye dark circles?

Yes — polynucleotides are one of the best treatments for improving under-eye skin quality, fine lines and crepey skin.

Can it help with hair loss?

Yes — when injected into the scalp, polynucleotides help stimulate hair follicles and improve scalp health.

All Treatments

Our Full Range of
Aesthetic Treatments

MORPHEUS8

HYDRAFACIAL

ANTI WRINKLE

LUMI EYES

Lip Filler

MARIONETTE LINES

The experience I had was nothing short of fabulous; the welcome from Marie and Elanda was perfect, they were great, beautiful, and super prepared to give you the best advice on how to resolve or mitigate the small aesthetic issues you want to improve! I trusted them to improve my situation with dark circles, and I must say that the result speaks for itself! Another magnificent thing was their availability to accommodate my schedule! In summary, a 5-star experience out of 5!! I highly recommend it!

I recently started my Morpheus& treatment plan here, and my beautician, Ellie, has been absolutely wonderful. She is incredibly patient and took the time to answer all my questions. The procedure itself was smoothly guided, and I felt truly looked after. I also received excellent skincare advice, which I found very helpful. I would definitely recommend M&K Aesthetics!

Marie and her team are not only welcoming and accommodating to everyone's needs but extremely professional and knowledgeable. I see elanda on a regular basis for skin boosters, Botox and filler. She is an incredibly qualified nurse who makes you feel at ease and keeps you informed throughout the whole process. Of course the best part is how easy it is to get along with her! I cannot recommend M&K enough! Thank you for always putting the client first!

I visited M&K Aesthetics this January and currently completing my IPL course with Lumecca. Marie is an excellent practitioner and my results are incredible so far. Wouldn't go anywhere else for my treatments.